The Horadic Cube is found in the beginning of Act 2. It is an essential part of quests but can also serve a purpose to manipulate items for your own purposes. Basically, you put certain items into the cube and hit the transmute button, which will check if there is a valid combination. If there is, all of the items in the cube will be lost and the new item will appear. The cube is also effective as extra storage, but be careful that you don't transmute on accident and lose all of the items inside of it. You can, however, get around this by not having a valid combination in the Cube, in which case hitting transmute will do nothing.

Horadic Cube Formulaes

Range Weapons and Ammo

Items	Results
2 quivers of Arrows	1 quiver of Bolts
2 quivers of Bolts	1 quiver of Arrows
1 quiver of Arrows + 1 Spear	1 bundle of Javelins
1 Axe + 1 Dagger + Stack of Throwing Knives	Stack of Throwing Axes

Ressistance Rings

Items	Results
2 Topazes + 1 Ring	Coral Ring (lightning resistance)
1 Ruby + 1 Ring + 4 Exploding Potions	Garnet Ring (fire resistance)
1 Emerald + 1 Ring + 4 Antidotes	Viridian Ring (poison resistance)
1 Sapphire + 1 Ring + 4 Thawing Potions	Cobalt Ring (cold resistance)

Potions

Items	Results
3 Mana Potions + 3 Heal Potions	1 Rejuvenation Potion
3 Mana Potions + 3 Heal Potions + 1 Gem	1 Full Rejuvenation Potion
1 Heal Potion + 1 Strangling Gas Potion	1 Antidote

Gems and Socketables

Items	Results
3 Gems of same grade and type	1 higher graded Gem of same type
6 Gems + 1 Sword	Socketed Long Sword

Magical Items

Items	Results
1 Perfect Gem of each type except skull + 1 Amulet	Prismatic Amulet (Resist All) [currently buggy]
3 Rings	1 random Amulet
3 Amulets	1 random Ring
3 Perfect Gems and Magical Item (Armor, Weapon, Jewelry)	Random magical item of the same type

Secrets

Items	Results
Town Portal Tome + Wirts Leg + defeat the current difficulty level (stand in the Rogue Encampment)	Moo Moo Farm